Remember “Super Size Me” with Morgan Spurlock, that self-sacrificing documentarian who ate nothing but McDonald’s food for a month?  (Ick - makes me shudder just thinking about it.)  Well, Gut (great name for a journal, don’t you think?) recently published an article that illustrates some of the biochemical effects of fast food consumption.  Subjects were instructed to eat at least two fast food meals a day and limit their daily exercise to less than 5000 steps (not a hell of a lot).  Even after just a week of this, over half the group showed abnormally elevated levels of a liver enzyme (ALT, for those who care).  These levels persisted for the rest of the 4-week study.  If I remember the documentary correctly, Spurlock experienced elevation in his liver enzymes, as well.  In fact, I think I remember his PCP seeming rather concerned by it.  Oh - and the average weight gain by the end of the study?  14 pounds.  As if we needed any more reason to shy away from those Big Macs.